BP1361

BP1361 is a small-molecule inhibitor targeting the bromodomain and extra-terminal (BET) family of proteins, particularly BRD4. These proteins play a key role in regulating gene expression, especially in cancers and inflammatory diseases. By blocking BET proteins, BP1361 disrupts the transcription of oncogenes and pro-inflammatory genes, showing potential in cancer therapy (e.g., leukemia, solid tumors) and inflammatory conditions.
Preclinical studies indicate BP1361 has strong binding affinity, good selectivity, and antitumor efficacy in vitro and in vivo. It is part of ongoing research to develop targeted epigenetic therapies with fewer side effects than conventional treatments. Clinical development status (e.g., phase trials) is not widely publicized, suggesting it remains in early-stage testing.
Key advantages include its oral bioavailability and potential for combination therapies. However, like other BET inhibitors, challenges may include drug resistance or toxicity. For precise details, consult recent literature or patent filings (e.g., WO2017/180381).

The BP1361 is a compact, high-performance buck converter IC with the following key features:
- Input Voltage Range: 4.5V to 18V
- Output Voltage: Adjustable (0.8V to 16V)
- Output Current: Up to 3A
- Efficiency: Up to 95%
- Switching Frequency: 500kHz (fixed)
- Protections: Over-current (OCP), over-temperature (OTP), and under-voltage lockout (UVLO)
- Package: SOP-8 (small footprint)
- Low Quiescent Current: ~50μA in shutdown mode
Ideal for battery-powered devices, industrial systems, and consumer electronics, the BP1361 offers stable power conversion with minimal external components. Its high efficiency and robust protections make it suitable for demanding applications.

The BP1361 is a 5-pin LED driver IC designed for constant current regulation in LED lighting applications.
Pin Functions:
1. VIN (Pin 1): Power supply input (4.5V–40V).
2. GND (Pin 2): Ground connection.
3. DIM (Pin 3): PWM dimming control input.
4. CS (Pin 4): Current sense input (connects to external resistor for current setting).
5. SW (Pin 5): Switching output (connects to inductor and LED load).
Key Features:
- Supports up to 1A output current.
- Built-in MOSFET and PWM dimming.
- High efficiency (up to 95%).
Applications:
- LED bulbs, strips, and general lighting.
The BP1361 simplifies LED driver design with minimal external components.

The BP1361 is typically available in a SOT-23-5 package, a compact surface-mount option with 5 pins. This package is widely used for small ICs, offering good thermal and electrical performance in minimal space. Suitable for various applications, it ensures easy integration into PCB designs.